F-18 FDOPA PET-CT for Movement Disorder Evaluation: Idiopathic Parkinson’s Disease and Atypical Parkinsonian Syndromes

Example is shown below-

Patient 1:

Clinical Presentation:

The patient has a history of antipsychotic treatment, prompting the clinician to investigate the possibility of drug-induced parkinsonism versus idiopathic Parkinson’s disease (IPD).


F-18 FDOPA PET-CT reveals normal DOPA uptake in the bilateral striatum, ruling out idiopathic Parkinson’s disease. The observed drug-induced symptoms and signs are likely the primary cause of the patient’s complaints.

Patient 2:

Clinical Presentation:

The second patient has been on and off syndopa treatment for the last two years, without a definitive diagnosis.


F-18 FDOPA PET-CT indicates severe reduced DOPA uptake in bilateral striatum, suggesting idiopathic Parkinson’s disease (IPD) or atypical parkinsonian syndrome. Further evaluation with FDG PET-CT is recommended, which may provide insights into specific subtype.

Scans performed at Department of Nuclear Medicine & PET-CT, Kamalnayan Bajaj Hospital, Chhatrapati Sambhajinagar (Aurangabad)

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