F-18 FDOPA PET-CT
F-18 FDOPA PET-CT for Movement Disorder Evaluation: Idiopathic Parkinson’s Disease and Atypical Parkinsonian Syndromes
Example is shown below-
The patient has a history of antipsychotic treatment, prompting the clinician to investigate the possibility of drug-induced parkinsonism versus idiopathic Parkinson’s disease (IPD).
F-18 FDOPA PET-CT reveals normal DOPA uptake in the bilateral striatum, ruling out idiopathic Parkinson’s disease. The observed drug-induced symptoms and signs are likely the primary cause of the patient’s complaints.
The second patient has been on and off syndopa treatment for the last two years, without a definitive diagnosis.
F-18 FDOPA PET-CT indicates severe reduced DOPA uptake in bilateral striatum, suggesting idiopathic Parkinson’s disease (IPD) or atypical parkinsonian syndrome. Further evaluation with FDG PET-CT is recommended, which may provide insights into specific subtype.